Statistical power of clinical trials has increased whilst effect size remained stable: an empirical analysis of 137 032 clinical trials between 1975-2017 | bioRxiv
Biomedical studies with low statistical power are a major concern in the scientific community and are one of the underlying reasons for the reproducibility crisis in science. If randomized clinical trials, which are considered the backbone of evidence-based medicine, also suffer from low power, this could affect medical practice.
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