I think the volatility of crypto currencies poses a problem for the loaning process. But I would much rather take a loan this way, than from the banks. At least here your asset can accumulate in value, and when your loan repayment is finished, your asset have accumulated in value, been in a beneficial HODL phase, and you will not be a loser but a winner in this situation. It which will be tax efficient as well to hold your asset for at least a year, so you have to choose your crypto well.