Older brain is made up of new neuroses!

in #brain3 years ago

According to a recent study, the human brain produces new cells even at the end of adulthood, even at the age of six.

Research shows how long human neuroscience can develop. In addition, in Alzheimer's disease, the process of generating new cells becomes ineffective. The latter finding may open a new horizon for the treatment of Alzheimer's disease.

The development of the nervous system often occurs in the fetus and upon the birth of a human baby, its nerve is almost complete.

But this is not the end of the story here. For the first time in the 8th decade, it is discovered that in mammals, after the adulthood and the nervous system develops, even in the old age of the animals new brain cells begin to develop in the brain.

Due to the limitations of the study of the human brain, it was not an easy task to determine how this new neuromuscular technique works and how long it lasts.

But in a new experiment led by molecular biologist Maria Lawrence Martin of Madrid Autonoma, Spain, researchers carefully examined the brain's cells in the brain and created new neurons (AHN) in the hippocampus region of the brain.

According to the researcher team's Lab website, "Our goal is to observe the technique of developing new neurons in the hippocampus region of the brain in the context of both physiological and pathological conditions."

"We are particularly interested in the potential for new neurosurgery in the hippocampus region of the brain of older people treating neurological devastating diseases such as Alzheimer's (AD) and other" Tao "protein diseases."

To find out if new neuroses originate in older people, scientists collect the collar sample called "Dentate Gyrus" (DG) from the hippocampus of four deceased persons.

These individuals, ranging in age from 5 to 6 years, died from various causes such as cancer, stroke, diarrhea and other serious diseases. The man was neurologically healthy before his death, and after his death his body was donated to science and research.

Finally, some important discoveries have been made about the development of the nervous system in the elderly. This pattern of development of the nervous system continues until the ninth decade of human life. Evidence for this has been found in thousands of cells called doublecrotein (DCX +) that express the DG nerve that is directly involved in nerve development.

In the research paper, the authors explain, "The overall data support the notion that the maturation of DCX + cell lines in human DG is irregular."

The presence of relatively immature DCX + nerves and early and endogenous expression of cells indicates that the maturation of these cells during human AHN is also long.

When the study team analyzed the brains of 12 to 4-year-old Alzheimer's patients, they found that as the disease progressed, the presence of immature DCX + nerves continued to decrease.

On the contrary, it can be seen that the rate of slowing down of neuronal development is much slower in neurologically healthy people due to aging. Those 6 neurologically healthy individuals had a reduced rate of DCX + cells in the DG banana as they were between the ages of 1 and 5.

However, researchers claim that the amount of DCX + cells in a neurologically healthy human of any age is higher than that of any boy with AD.

"These data support the notion that AD is a condition that is physiologically different from puberty. It is normal to decrease the number of DCX + cells due to aging. But individual neurological diseases such as AD are responsible for significantly destroying the number of immature nerve cells. "

Researchers also say that the neurological issue of AD sufferers suffers from the early stages of the disease, even before symptoms such as nervous system cramps and aging complications are revealed.

We still need a lot of research to understand why this happens. However, the research team suggested that the damage caused by AHN should be identified through a risk-free process so that doctors can diagnose the disease without having to cure the early symptoms of AD.

To succeed in this goal, further research is needed. But our recent achievement is a huge achievement.

Researchers conclude that "our data show that, in physiological and pathological conditions, human colonization and the dentate gyrus (DG) exist in the 8th decade of human life".

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