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It all depends of what you want, what coin, what gpu, what price range, what os, what electricity price you got, what hardware availability you got etc.

If you can't decide what coin then look the major ones.

Coin Marketplace

STEEM 0.25
TRX 0.20
JST 0.038
BTC 93413.26
ETH 3418.78
USDT 1.00
SBD 3.80