The 2017 run up was purely speculation based (had no real ties to development, use-cases, active users...), any future run ups in the crypto space will likely be quite different then the 2017 one and will require actual advances in development, actual real-world use cases, and actual increases in daily active users to cement the validity of each coin beyond purely speculation.

Basically I don't think the cryto space is dead in any sense of the word but actual valid uses will be needed before the space will be able to explode upwards again like it has in the past.