You absolutely right , no one in this life pass without this four sights which lead Buddha his realization of the impermanence and ultimate dissatisfaction of conditioned existence- this are
The truth of suffering (Dukkha)
The truth of the origin of suffering (Samudāya)
The truth of the cessation of suffering (Nirodha)
The truth of the path to the cessation of suffering (Magga).

But some people lost hope and they stop the cessation of life by killing them self.
If we lost Hope we lost everything. This world is a transition and we have to cross over.
" Strength is life and Weakness is Death". Swami vivekananda.