Definition of key terms declared in the statements of the following text.
REDUCTION: A chemical reaction where a molecule is reduced in molecular weight and structure.
OXIDATION: A chemical reaction where a molecule reacts with O2 (Oxygen).
REDOX: A term used in chemistry to collectively designate the cyclic reactions of reduction and oxidation. A process by which molecules degrade, develop and stabilize within a set of chemical conditions.
HYDROPHOBIC: A term designating the insolubility of a substance in water. The term is also used to describe the chemical environment within a biochemical structure such as a receptor site, cell, etc.
HYDROPHILIC: A term designating the solubility of a substance in water. The term is also used to describe the chemical environment within a biochemical structure such as a receptor site, cell, etc.
THCA: Tetrahydrocannabinolic Acid.
THC: Delta-9 Tetrahydrocannabinol.
THCA undergoes an organic chemical process known as REDUCTION (decarboxylation) to form the THC molecule.
THC reacts with O2 (Oxygen) during the organic chemical process designated as OXIDATION which produces the CBN molecule.
REDUCTION and OXIDATION are collectively designated by chemistry as REDOX reactions. The cycle of REDOX reactions in the case of phyto-cannabinoid chemistry, take the hydrophobic forms of phyto-cannabinoids to their hydrophilic state.
To better understand how phyto-cannabinoids interact with cannabinoid receptors in human biochemistry, it is necessary to consider the chemical properties of the receptor sites.
CB1 receptors have the chemical property of being HYDROPHOBIC. For a cannabinoid molecule to interact with the receptor it must also be HYDROPHOBIC (insoluble in water).
CB2 receptors have the chemical property of being HYDROPHILIC. For a cannabinoid molecule to interact with the receptor it must also be HYDROPHILIC (soluble in water).
While there are molecules which create exceptions to the two general rules which are previously stated, it is important to first understand the most common cases which allow interaction with the receptor sites based on their chemical properties.