Myelin as a conductor, not an insulator

in #biology4 years ago (edited)

"Due to the presence of the insulating myelin sheath at internodes and voltage-gated sodium channels at nodes, the action potential in myelinated nerve fibers jumps from one node to the next. This mode of travel by the action potential is called "saltatory conduction" and allows for rapid impulse propagation. "

The nerve impulse "leap" across the myelinated internodal segment is often attributed to insulating capacity of myelin somehow speeding up the impulse, without explaining how the impulse propagates, other then that it involves switch between potassium adsorption to sodium adsorption and the "action potential" voltage that results as sodium flows in faster than potassium flows out (following concentration gradient of free sodium vs adsorbed potassium. ) The alternative to that myelin somehow speeds things up by insulation, is that myelin is itself a conductor of nerve impulses, the current (whatever it is) during saltatory conduction passes through the myelin laminae, not through the axon.

The channel myelin provides to conduct nerve impulses could be not through the cell itself, but through the extracellular space between the laminae, here shown by Hirano in 1969 (contrast provided by lanthanum. ) Gerald Pollacks polarized water structure that forms at contact surfaces could provide a high density of hydronium ions between the laminae (consequently, a low pH), and like any ion, these hydronium ions would be well suited to conduct electricity.

channels.png

Synapses

Hirano, A., & Dembitzer, H. M. (1969). The transverse bands as a means of access to the periaxonal space of the central myelinated nerve fiber. Journal of ultrastructure research, 28(1), 141–149. https://doi.org/10.1016/s0022-5320(69)90012-4

Coin Marketplace

STEEM 0.25
TRX 0.11
JST 0.032
BTC 62432.37
ETH 3003.22
USDT 1.00
SBD 3.78