Flagging Intersting research #revoking memory loss

Hello Steemers,

Today came with a flagging interesting research that is GENETICS- FIGHTING ALZHEIMER'S.
I was reading report published in 'cell report' and found really interesting and knowledgeable so sharing with you all.

In the BRAIN of Alzheimer's patients many of the genes required to form new memories are shut down by a genetic blockade, contributing to the cognitive decline in those patients.

MIT researchers have now shown that they can reverse that memory loss in mice by interfering with the enzyme, known as HDAC2, turns genes off by condensing them so tightly that they can't be expressed.
For several years, scientists and pharmaceutical companies have been trying to develop drugs that block this enzyme, but most of these drugs also block other members of the HDAC [Histone deacetylases (EC 3.5.1.98, HDAC)] family, which can lead to toxic side effects. The MIT team has now found a way to precisely target HDAC2, by blocking its interaction with a binding partner called Sp3.

"This is interesting and exciting because for the first time we have found a specific mechanism by which HDAC2 regulates synaptic gene expression"

"we think that HDAC2 serves as a master regulator of memory gene expression, and during Alzheimer's disease it's elevatedso it causes an epigenetic blockade of the expression of all these genes.

Thank you for reading!!
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Have a nice weekend!
Greetings from
VINU (miracle boy)