Israel's Netanyahu attacks 'dangerous Iranian tiger'
Benjamin Netanyahu said Israel would "not allow Iran's regime to put a noose of terror around our neck".
Mr Netanyahu drew a parallel between the 1938 Munich Agreement, seen as a failed attempt to appease Nazi Germany, and the 2015 Iran nuclear deal.
He said the deal had only "unleashed a dangerous Iranian tiger".
Mr Netanyahu accused Iran's foreign minister and representative in Munich, Mohammad Javad Zarif, who is due to address delegates later on Sunday, of being the "smooth-talking mouthpiece of Iran's regime... [who] lies with eloquence".
He said Iran was falsely denying that it sent a drone into Israeli territory last week which was shot down by Israeli forces.
Why the recent spike in tensions?
The immediate trigger is last week's confrontation - the first known direct engagement between the Israeli and Iranian militaries.
Israel launched raids against Iranian targets in Syria after saying it had intercepted an Iranian drone crossing the Syria-Israel border.
During the offensive, an Israeli F-16 fighter jet was shot down by Syrian air defences, its pilots ejecting in northern Israel.
It was believed to be the first time Israel had lost a jet in combat since 2006.
After the attack, Mr Netanyahu said Iran had "brazenly violated Israel's sovereignty" and vowed that Israel would defend itself.